HPV (Human Papillomavirus)

KEY POINTS

  1. Venereal warts on skin around genitals or internally on female uterine cervix (although HPV disease can be very subtle and difficult to detect)

  2. Prevalence: Worldwide

  3. HPV is the most common STD in the U.S.

  4. HPV vaccine is not intended for treatment of active genital warts or cancer.

  5. Target: 9 to all adults, males and females, who are or will be sexually polygamous to protect against genital warts and cervical, vaginal, vulvar cancer, and head and neck cancers.

Disease: A sexually transmitted viral infection of the genital areas

Complications: Cervical cancer – 3700 U.S. deaths from this each year (233,000 worldwide)

Prevalence:

  1. Worldwide

Transmission: Genital and skin-to-skin contact

Treatment: Cryotherapy of warts

Prevention:

1. Safe sex with barrier methods

2. Vaccine (killed/Gardasil)

a. 0.5cc, intramuscularly

b. Primary Series: 3 doses, at time “0”, 1 – 2 mo’s, and 6 mo’s

c. Side-Effects;

i. Mild-moderate: Injection site pain, fever, syncope, headache, nausea, joint ache, muscle ache, malaise

ii. Serious (< 0.1%): asthma, diarrhea, hypertension, headache

d. Precautions/Contraindications

i. HPV vaccine is not intended for treatment of active genital warts or cancer.

ii. Postpone vaccination when moderately ill.

iii. Systemic allergic reactions to yeast, aluminum, or polysorbate contraindicate the vaccine.

iv. Patients should sit or lie down for 15 min. after vaccination to minimize risk of passing out.

v. May be given to immune-compromised.

vi. Breastfeeding is not a contraindication.

vii. Not recommended with pregnancy (not enough data to establish safety).

e. Targets

i. 9 – adults, males and females, who are or will be sexually polygamous to protect against genital warts and cervical, vaginal, vulvar and head and neck cancers.

Access the VIS Sheet here

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